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#Antibiotic #Drug

Antibiotic Classes

Jan. 21, 2024

Cell wall synthesis inhibitors Beta lactams Penicillins - relatively narrow spectrum Cephalosporins Carbapenems Monobactams Glyco…

#ID #Respiratory #Rheumatology

Mycobacterium Tuberculosis

Jan. 21, 2024

Can become dormant or disseminate depending on host immune system Risk at extremes of ages + immunocompromised 90% of primary infections asymp…

#Respiratory

Pneumonia

Jan. 21, 2024

Two anatomical patterns: bronchopneumonia following bronchi and lobar pneumonia 90% S. pneumoniae Bacterial Usually rapid onset Productive…

#ENT

Ear Infections

Jan. 21, 2024

Otitis Externa - 90% bacterial, S. aurerus, becomes maligant/life threatening when spreads to skull base Otitis Media - middle ear infection, viru…

#Symptom

Sore throat

Jan. 21, 2024

Tonsillitis & Pharyngitis - virus, Group A Strep (S. pyogenes) Centor criteria (if bacterial): Tonsillar exudate Tender anterior cervi…

#Respiratory

Pleural neoplasms

Jan. 21, 2024

Primary - benign rare, malignant mesothelioma common, others uncommon Secondary malignant - breast, lung, others common Malignant mesotheli…

#Respiratory

Pleural fibrosis

Jan. 21, 2024

Usually secondary to pleural inflammation/ asbestos associated Parietal low level asbestos dust exposure asymptomatic may be visible on …

#Respiratory

Pneumothorax

Jan. 21, 2024

Closed Not exposed to outside world Usually not traumatic Lung air is drawn into pleural cavity during inspiration, reducing potential lung…

#Cardiovascular #Respiratory

Pleural Effusion

Jan. 21, 2024

Transudate tame - fluids leak from intact vessels so low protein  Exudates extreme - from pathological capillaries so high protein   …

#Respiratory

Lung Tumours

Jan. 21, 2024

Primary Lung Tumours 90% are carcinomas Non-small cell carcinoma 85% squamous cell carcinoma 20% adenocarcinoma 30% large cell ca…

#Respiratory

Cystic Fibrosis

Jan. 21, 2024

Abnormally thickened mucous due to chloride channel deletion of a phenylalanine residue - all tubes/mucous places have issues Dehydrated mucus t…

#Respiratory

Hypersensitivity Pneumonitis

Jan. 21, 2024

Inflammatory and fibrotic bronchiolar response to inhaled antigens that are not removed Chronic inflammation around bronchioles sometimes with i…

#Respiratory

Sarcoidosis

Jan. 21, 2024

Multisystem granulomatous disease that most commonly involves lymph nodes and lungs 20-60 most common, all ages & genders globally more in s…

#Respiratory

Pneumoconiosis

Jan. 21, 2024

Lung damage secondary to particle inhalation: coal dust, silica, asbestos Occupational exposure Particles ingested by macrophages, trigger fib…

#Respiratory

Idiopathic Pulmonary Fibrosis

Jan. 21, 2024

Progressive patchy scarring especially lower zones that is fatal Repeated epithelial injury $\rightarrow$ inflammation and fibrosis Dry cough …

#Respiratory

Bronchiectasis

Jan. 21, 2024

Permanent dilation of bronchi and bronchioles due to wall damage secondary to chronic necrotising infection Usually triggered by obstruction (t…

#ENT #Neurology

Auditory pathway

Jan. 21, 2024

Ossicles: Malleus, Incus, Stapes (MIS) Oval window transmits the waves, round window releases them Hair cells sit on basilar membrane with tip…

#Neurology #Ophthalmology

Visual pathway

Jan. 21, 2024

All info goes via lateral geniculate nucleus of thalamus - Upper visual field goes to lower bank of calcarine sulcus and vice versa

#Neurology

Cerebellum

Jan. 21, 2024

Always and completely ipsilateral Vestibulocerebellum (Archicerebellum) - Flocculonodular lobe, part of vermis. Balance and eye movements Sp…

#Neurology

Spinal reflexes

Jan. 21, 2024

Reflex Sensory afferent Proposed function Myotactic (stretch) reflex Muscle spindle - 1a afferent Muscl…

#Neurology

Autonomic division

Jan. 21, 2024

Only carried within segmental spinal nerves: Sympathetic - T1-L2, highly organised, widespread effect. Ganglion in sympathetic chain Par…

#Acute #Cardiovascular

Intermediate Life Support

Jan. 21, 2024

  Patients in VF/pulseless VT should receive one shock followed by two minutes of CPR. If they are witnessed having the cardiac arrest and ar…

#Cardiovascular #Dermatology #Nephrology #Rheumatology

Different vasculitis

Jan. 21, 2024

Vasculitis Vessels Lab Findings Key Features Henoch-Schonlein Purpur…

#Endocrinology

Graves' disease

Jan. 21, 2024

Inappropriate stimulation of thyroid gland by anti-TSH auto-antibody Propanolol used to provide symptomatic relief when waiting for treatment

#Acute #Psychiatry

Salicylate overdose

Jan. 21, 2024

Tinnitus, anxiety, diaphoresis Respiratory alkalosis followed by metabolic acidosis Give activated charcoal

#Symptom

Hypomagnesemia

Jan. 21, 2024

​​​​​​​Cofactor for ATP, neuromuscular excitability, enzyme function, regulates ion channels Required for PTH release Associated with other el…