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#Acute #Psychiatry

Benzodiazepine overdose

Jan. 21, 2024

Hypotension, bradycardia, respiratory depression and coma Flumazernil used to reverse

#Acute #Psychiatry

Tricyclic antidepressant overdose

Jan. 21, 2024

TCA examples: amitriptyline, clomipramine, dosulepin, imipramine, lofepramine and nortriptyline   Overdose sign and symptoms: …

#Antibiotic #Drug

Gentamicin

Jan. 21, 2024

Drug Class Aminoglycoside Mechanism Bactericidal  Typical Dose IV or drops only - 3-7mg/kg in 3 …

#Acute #Cardiovascular

Hyperkalaemia

Jan. 21, 2024

Causes  Medications ACEis ARBs Potassium sparing diuretics Trimethoprim Beta blockers Suxa…

#ID #Orthopaedics

Necrotising fasciitis

Jan. 21, 2024

Rapidly progressive, live threatening, tracking along fascia cutting off blood supply \(\rightarrow\) necrosis Type 1: Synergistic/poly-microbi…

#Surgery

Graft rejection

Jan. 21, 2024

  Acute rejection occurs within 6 months  Typically presentings with signs and symptoms of infection Confirm via biopsy and incre…

#Oncology

Cancer histology/pathology

Jan. 21, 2024

Reed-Steinberg cells - Hodgkin's lymphoma Rouleaux formation - multiple myeloma Auer rods - AML

#ID #Rheumatology

Kawasaki disease

Jan. 21, 2024

Usually affects children <5 It is a form of vasculitis, with fever, rash, and glandular swelling Any fever lasting 5+ days think Kawas…

#Nephrology #Rheumatology

Anti-glomerular basement membrane

Jan. 21, 2024

Anti-GBM previously known as Goodpasture's syndrome haemoptysis + haematuria + proteinuria

#ID

Infectious mononucleosis

Jan. 21, 2024

caused by EBV lymphadenopathy and splenomegaly

#Endocrinology #OBGYN

Polycystic ovary syndrome

Jan. 21, 2024

Endocrine disorder characterised by hyperandrogenism + insulin resistance \(\uparrow\) LH \(\downarrow\) FSH \(\rightarrow\) hyperand…

#OBGYN

Menorrhagia

Jan. 21, 2024

First line is IUS

#Drug

Fluoxetine

Jan. 21, 2024

Can cause hyponatremia with increased urinary sodium through SIADH

#Drug

Fluconazole

Jan. 21, 2024

Can increase INR

#Neurology

\(\uparrow\) ICP signs

Jan. 21, 2024

Long intracranial course of abducens (CN VI) makes it suseptible to damage early in increased ICP  Innervates lateral rectus so the affecte…

#Antibiotic #Drug

Animal bite antibiotics

Jan. 21, 2024

  Prophylactic antibiotic dose should be given in human, dog + cat bites 1st line - co-amoxiclav 2nd line - doxycycline & metroni…

#Cardiovascular #Neurology

Stroke symptoms per artery

Jan. 21, 2024

    PICA - vertigo, vomiting dysphagia, ipsilateral facial pain & temperature loss, contralateral limb pain & t…

#Cardiovascular #Drug

Dual antiplatelet therapy

Jan. 21, 2024

Aspirin + ticagrelor for low bleeding risk Aspirn + clopdogrel for high bleeding risk  Prasugrel used when patients a…

#Haem

Anaemia

Jan. 20, 2024

Disease Iron TIBC Ferritin Iron deficiency \(\downarrow\) \(\uparrow\) \(\downarrow\) …

#Antibiotic #Drug

Doxycycline

Jan. 20, 2024

Drug Class Tetracycline Mechanism Bacteriostatic - inhibit protein synthesis Typical Dose 500mg BD …

#Cardiovascular #Drug

Simvastatin

Jan. 20, 2024

Drug Class Statin Mechanism Reversibly inhibits HMG CoA reductase - the rate limiting enzyme in cholesterol synt…

#Nephrology

Alport syndrome

Jan. 20, 2024

Alport = All ports affected (eyes, ears, urine) Faulty gene causing a type 4 collagen defect Characterized by glomerulonephritis, end-stage k…

#Haem

Factor V leiden

Jan. 20, 2024

Resistance to activation of protein C

#Oncology

Hodgkin's Lymphoma

Jan. 20, 2024

Best prognosis is lymphocyte pre-dominant type It's more common in older people but can occur in young people. The main difference between…

#Endocrinology #OBGYN

Hypothyroid in pregnancy

Jan. 20, 2024

Increase levothyroxine in pregnancy (+25-50mg)

#Neurology #Surgery

Stroke Treatment Choice

Jan. 20, 2024

Thrombectomy + thrombolysis for people with ischaemic stroke <6h. Thrombectomy if limited infarct