ALPHA
Viral hepatitis
Hepatitis A Faecal-oral route More common in countries with poor hygiene Usually passes after a few months…
Continue readingLiver failure
Development of coagulopathy INR >1.5 Encephalopathy May occur suddenly in the previously healthy liver Hyper Ac…
Continue readingJaundice
Classified by the site of the problem - pre-hepatic, hepatocellular or cholestatic/obstructive Or by the type of circulating bilirubin - conjugate…
Continue readingCirrhosis
Irreversible liver damage - loss of normal hepatic architecture Most commonly caused by alcohol abuse or HBV/HCV Leuconychia from the hy…
Continue readingAscites
Sodium and water retention - peripheral arterial vasodilation which causes a reduction in BV. This reduction activates the RAAS promoting ret…
Continue readingSpontaneous Bacterial Peritonitis
A form of peritonitis, usually seen in patients with ascites secondary to liver cirrhosis Abdominal pain and fever in patients with ascites D…
Continue readingParacetamol Overdose
Paracetamol is absorbed from the gut and rapidly metabolised by the liver. A toxic metabolite is produced and glutathione is required to continue the…
Continue readingGilbert Syndrome
Gilbert's syndrome inherited metabolic disorder with mild and intermittent elevation of unconjugated (indirect) bilirubin levels, due t…
Continue readingPrimary sclerosing cholangitis vs biliary cholangitis
Both are autoimmune disease where the the bile ducts are affected. Primary Sclerosing Cholangitis Intra and extra hepatic bile duc…
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