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#Cardiovascular #Drug

Isosorbide Mononitrate

April 8, 2024

Drug Class Nitrate Mechanism Metabolised to NO in smooth muscle cells Causes vascular smooth muscle relaxa…

#Cardiovascular #Drug

Losartan

April 8, 2024

Drug Class Angiotensin 1 blocker Mechanism Displace angiotensin II from the angiotensin I receptor Typica…

#Cardiovascular #Drug

Ramipril

April 8, 2024

Drug Class ACE inhibitor Mechanism Inhibits angiotensin converting enzyme - ↓ angiotensin II synthesis…

#Cardiovascular #Drug

Diltiazem

April 8, 2024

Drug Class Calcium channel blocker Mechanism Interfere with the inward movement of calcium ions into cells …

#Cardiovascular #Drug

Atenolol

April 8, 2024

Drug Class Beta blocker Mechanism Acts on β1 receptors in the heart ↓ HR and force of …

#Cardiovascular #Drug

Spironalactone

April 8, 2024

Drug Class Potassium sparing diuretic Mechanism Aldosterone antagonist Competes for receptors in DCT…

#Cardiovascular #Drug

Bendroflumethiazide

April 8, 2024

Drug Class Thiazide diuretic Mechanism Inhibits Na/Cl reabsorption in distal tubules Stimulate K excr…

#Cardiovascular #Drug

Furosemide

April 8, 2024

Drug Class Loop diuretic Mechanism Inhibits Na/K/2Cl pump in ascending loop of Henle  Inhib…

#Drug #Gastroenterology

Mesalazine

April 8, 2024

Drug Class Aminosalicylates Mechanism Release 5-aminosalicyclate acid in the bowel Typical Dose 2.4-4…

#Drug #Gastroenterology

Senna

April 8, 2024

Drug Class Stimulant laxative Mechanism Hydrolysed in colon to stimulate myenteric plexus, smooth muscle activity …

#Drug #Gastroenterology

Loperamide

April 8, 2024

Drug Class Anti-diarrhoeal agent Mechanism Acts on opioid receptors in myenteric plexus to inhibit peristalsis (inhib…

#Drug #Gastroenterology

Omeprazole

April 8, 2024

Drug Class Proton pump inhibitor Mechanism Inhibits gastric acid secretion by dose-dependent inhibition of proton pum…

#Drug #Gastroenterology

Ranitidine

April 8, 2024

Drug Class H2 Antagonist Mechanism Competitively inhibits histamine actions at all H2 receptors, mainly inhibiting ga…

#Drug #Gastroenterology

Gaviscon

April 8, 2024

Drug Class Antacids Mechanism Weak alkali to neutralise stomach acid Alginate component ↑ s…

#Respiratory

Lung abscess

April 6, 2024

Subacute productive cough, foul-smelling sputum, night sweats → ?lung abscess

#Cardiovascular

Determining the valve

April 6, 2024

R(ight sided murmurs) I(nspiration) L(eft sided murmurs) E(xpiration) For IVDU, the first valve that the venous system interacts with is the tr…

#Drug

Thiazide diuretics

April 6, 2024

Commonly used in management of hypertension and heart failure Exacerbate gout by increasing serum uric acid levels

#Gastroenterology #Hepatology

Spontaneous Bacterial Peritonitis

April 6, 2024

A form of peritonitis, usually seen in patients with ascites secondary to liver cirrhosis Abdominal pain and fever in patients with ascites D…

#Haem

Haemochromatosis

April 5, 2024

Iron storage disorder - doesn't raise circulating blood iron Raised transferrin saturation and ferritin, with low TIBC Chronic progressi…

#Antibiotic #Drug

Co-amoxiclav

April 5, 2024

Broad spectrum antibiotic - combination of amoxicillin and clavulanic acid (beta lactamase inhibitor) RTIs, UTIs, skin and soft tissue infection…

#ENT #Gastroenterology

Pharyngeal pouch

April 5, 2024

dysphagia regurgitation halitosis age 70+ surgical resection

#Drug #Gastroenterology

Sulphasalazine

April 5, 2024

Aminosalicylate - to reduce inflammation. Used in the treatment of ulcerative colitis and rheumatoid arthritis Can cause haemolytic anaemia wi…

#Gastroenterology

Malnutrition

March 20, 2024

Nutrition via gastrointestinal tract - enteral feeding Mouth NG Percutaneous endoscopic gastrostomy (PEG) - tube from the surface of abdo t…

#Gastroenterology #Surgery

Gastrointestinal perforation

March 20, 2024

Four mechanisms that lead to perforation: Ischemia (bowel obstruction, necrosis) Infection (appendicitis, diverticulitis) Erosion (malignan…

#Drug #Symptom

Steroid side effects

March 20, 2024

Mood swings + emotional changes Weight gain - increased appetite High BP Increased risk of infection - suppressed immune system  Glau…

#Drug #Haem

Warfarin

March 20, 2024

Vitamin K antagonist - vitamin K dependent clotting factors: II, VII, IX, X and protein C and S Indications: Mechanical heart valves Valvu…

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Here's a collection of short useful bits of info that can be looked up easily. These usually don't fit anywhere else but are important.

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  1. #Acute
  2. #AIassisted
  3. #Antibiotic
  4. #Cardiovascular
  5. #Dermatology
  6. #Drug
  7. #Endocrinology
  8. #ENT
  9. #Examination
  10. #Geriatrics
  11. #Haem
  12. #Incomplete
  13. #ID
  14. #MSK
  15. #Nephrology
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  18. #Ophthalmology
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  22. #Radiology
  23. #Reproductive
  24. #Respiratory
  25. #Rheumatology
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  27. #Symptom
  28. #Urology
  29. #Paediatrics
  30. #OBGYN
  31. #Gastroenterology
  32. #Genetics
  33. #Neonatology
  34. #Hepatology