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#ID #Paediatrics

Varicella zoster virus

evan March 19, 2024

Causes chicken pox. Highly contagious, generalised vesicular rash. Most common in children. One episode develops immunity to the virus.

Patients become symptomatic 10 days to 3 weeks after exposure. They stop being contagious after all the lesions have crusted over - usually around 5 days after rash appears 

The virus can lie dormant in the sensory dorsal root ganglion cells and cranial nerves and reactivate later in life as shingles or Ramsay Hunt syndrome

  • Conservative management - lotion and antihistamines for itching.
  • Children should be kept off school and avoid pregnant women and immunocompromised people until not 

 

Pregnancy

Those who are known to be immune are not at risk.

  • Chicken pox in pregnancy before 28 weeks gestation can cause development problems in the foetus - congential varicella syndrome.
  • Varicella zoster immunoglobulins can be given to protect against the virus after exposure.
  • Aciclorvir can also be considered within 24 hours of exposure

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