UTI in Pregnancy

UTI in pregnancy should always be treated even if asymptomatic

First Trimester

• Trimethoprim should be avoided as it is teratogenic (folate antagonist with can lead to neural tube defects)
• Nitrofurantoin for 7 days - cefalexin 2nd line

Second Trimester

 

Third Trimester

• Nitrofurantoin should be avoided at term due to risk of neonatal haemolysis and therefore cefalexin is the best option here.