Osteoporosis

Decreased bone mass + deranged bone microarchitecture = failure of structural integrity

• Aging, glucocorticoids - DEXA + XR for diagnosis

Common sites of fragility fracture - spine, neck of femur, wrist

FRAX calculation tool for risk

Treat with antiresorptive (RANK-Li, bisphosphonates) + anabolic (PTH analoge)