Rapidly progressive, live threatening, tracking along fascia cutting off blood supply \(\rightarrow\) necrosis
- Type 1: Synergistic/poly-microbial, Streps, anaerobes. Risk factors DM, Obesity, immunosuppression, elderly
- Type 2: Group A strep (S. pyogenes), younger age, associated with cut/injury. "Dish water" exudate. Treatment: surgical emergency