#Drug #Endocrinology

Levothyroxine

evan April 12, 2024

Drug Class	Thyroid hormone
Mechanism	Mimics endogenous thyroxine
Typical Dose	Initially 25-50 micrograms OD adjusted in 25 microgram steps according to symptoms
Indications	Hypothyroidism
Contra-indications	Thyrotoxicosis
Side-effects	Hyperthyroid symptoms if over adjusted Rare: cardiac dysrhythmias, MI, angina,
Interactions	Warfarin: ↑ effect of warfarin
Elimination
Additional Notes	TFTs must be monitored every 3 months

Increase dose by 25-50 in pregnancy

April 30, 2024, 2:59 p.m.