ALPHA
#Endocrinology #Genetics

Hypoparathyroid

evan March 4, 2024

Underproduction of parathyroid hormone despite low calcium. Much rarer than hyperparathyroidism 

Primary

Causes

  • DiGeorge syndrome
  • Autosomal dominant hypoparathyoidism
  • Pseudohypoparathyroidism Type 1A - bones + kidney don't respond to parathyroid hormones - defective parathyroid hormone receptor
  • Surgical damage to the gland after thyroidectomy

Symptoms of hypocalcemia and hyperphosphatemia (table)

 

Secondary

Depression due to chronic hypocalcaemia, would likely accompanied by signs of hypocalcaemia

Comments