- Plasma volume \(\uparrow\) 50%, RBC \(\uparrow\) 25%, so dilutation occurs, maximally at 32 weeks.
- Increases folic acid requirements
- Leukocytosis - mainly neutrophilia (left shift may also been seen more immature cells)
- Thrombocytopenia - no pathological significance and recovers
- Pro-thrombotic state however - coagulation factor increase, and clot breakdown decreases
ALPHA