Cushing's Syndrome

Where too much cortisol is present. Dynamic suppression test needed - dexamethasoneshould reduce ACTH and cortisol. Classic features - moon face central shoulders, purple striae

Disease

Pituitary tumour releasing ACTH causes increased cortisol release

Syndrome

• Any other cause - steroids, adrenal cortex tumour, ectopic tumour eg small cell lung carcinoma