Immune mediated enteropathy when ingestion of wheat, rye or barley - anything containing gliadin
- Increased CD8+ intraepithelial lymphocytes
- Villous atrophy, crypt elongation
Non-invasive serologic tests usually performed before biopsy - IgA to TTG or IgA/G to gliadin. Tissue biopsy gold standard
Treatment with gluten free diet