#Drug #Endocrinology

Carbimazole

evan April 12, 2024

Drug Class	Anti-thyroid
Mechanism	Inhibits thyroid peroxidise which is necessary for thyroid synthesis
Typical Dose	15-40mg up to 60mg for blocking therapy
Indications	Hyperthyroid
Contra-indications	Severe blood disorders High caution in pregnancy - congenital malformations esp in 1st trimester
Side-effects	Common: GI disturbance, headache, skin rash, pruritis, joint pain Rare: agranulocytosis, jaundice, alopecia
Interactions
Elimination
Additional Notes	Regular monitoring is essential. Graves treatment should continue for at least a year.