ALPHA
#Cardiovascular #Drug

Aspirin

evan April 8, 2024
Drug Class Anti-platelet agent
Mechanism Irreversible COXI and COXII inhibitor
Typical Dose 75g OD - 300mg loading in MI
Indications
  • Secondary prevention for CVD
  • ACS
  • Ischemic stroke/TIA
  • OTC pain relief
Contra-indications
  • Active bleeding
  • Peptic ulcer
  • Haemophilia
  • Breast feeding 
  • Pregnancy during the third trimester
Side-effects
  • Bronchospasm
  • GI haemorrhage
Interactions  
Elimination  
Additional Notes Do not give to anyone under the age of 16 esp after a viral infection - Reye's syndrome. Risk of hepatic and cerebral swelling. 

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