ALPHA
| Disease | Iron | TIBC | Ferritin |
|---|---|---|---|
| Iron deficiency | \(\downarrow\) | \(\uparrow\) | \(\downarrow\) |
| Anaemia of chronic disease | \(\downarrow\) | \(\downarrow\) | \(\uparrow\) |
| Chronic haemolysis | \(\uparrow\) | \(\downarrow\) | \(\uparrow\) |
| Haemochromatosis | \(\uparrow\) | \(\downarrow\) or \(\leftrightarrow\) | \(\uparrow\) |
| Pregnancy | \(\uparrow\) | \(\uparrow\) | \(\leftrightarrow\) |
| Sideroblastic anaemia | \(\uparrow\) | \(\leftrightarrow\) | \(\uparrow\) |
Haemolytic - macrocytic \(\uparrow\) reticulocytes \(\uparrow\) bilirubin
- Things wrong inside cell - sickle cell, G6PD def, thalassaemia
- Things wrong with RBC membrane - spherocytosis elliptocytosis
- External things wrong - antibodies, heart valves, drugs, vascular